Skip to main content
. 2022 May 11;13:2592. doi: 10.1038/s41467-022-30248-0

Fig. 3. Comparisons of different inflation factor estimation methods.

Fig. 3

The first three columns show the inflation factors estimated using different methods. The dashed lines are the fitted lines in the inflation factor estimation. The fourth column shows boxplots of the estimated inflation factors using simulated P values under the null hypothesis (n = 1000 independent replicates). The red circle indicates the mean value, the center line indicates the median value, the bounds of the box covers data between 25th and 75th percentile. The outliers are points above or below 1.5 times the interquartile range starting from the 75th or 25th percentile. If there is no outlier, the whisker defines the minima or maxima, otherwise it is 25th percentile minus 1.5 times interquartile range or 75th percentile plus 1.5 times the interquartile range. a Results based on the central nervous system (CNS) cancer cohort and the two-sided Fisher’s exact test (FET). b Results based on the acute lymphoblastic leukemia (ALL) cohort and the two-sided FET. c Results based on the CNS cohort and the two-sided Cochran–Mantel–Haenszel exact test (CMH) stratified by ethnicities. d Results based on the ALL cohort and the two-sided CMH stratified by ethnicities.