Table 3.

Interventions proposed by stages.

	Lieberman et al. [13]	Agius et al. [7]	McGorry et al. (2010)	Cornblatt [33]	Carrion et al. [36]
Stage 0	Potential for gene therapy		Psychoeducation
Stage 0a				Psychotherapy	Antidepressant
Stage 0b				Antipsychotics Antidepressant Psychotherapy	Antipsychotics Antidepressant
Stage 0c				Antipsychotics Antidepressant Psychotherapy
Stage 1	Atypical antipsychotics Stress reduction therapy	Antipsychotics Antidepressant Cognitive therapy	Family psychoeducation Substance abuse reduction	Antipsychotics Psychotherapy
Stage 1a			Counseling and problem solving Exercise
Stage 1b			CBT Cognitive intervention
Stage 2	Antipsychotics	Optimize medication Psychosocial interventionsa	Family psychoeducation CBT Substance abuse reduction Atypical antipsychotics Antidepressant/mood stabilizers Work rehabilitation
Stage 3	Antipsychotics and potential experimental agents as adjunctive treatment	Optimize medication: clozapine Psychosocial interventionsa Relapse prevention
Stage 3a			Medical strategies Psychosocial intervention
Stage 3b			Relapse prevention
Stage 3c
Stage 4			Clozapine

CBT cognitive behavioral therapy.

^aFamiliy interventions, Compliance therapy, Relapse intervention, Psychoeducation.