Table 3.
Direct costs by VSP status
| Author (date) Study ID |
Data collection | Subgroup | n | Time point | Unit | Costs in local currency not inflated | Costs in GBP inflated to 2021 | ||
|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | Median (IQR) | Mean (SD) | Median (IQR) | ||||||
|
Rivero-Arias et al. (2009) [32] ISATa |
1997–2007 | With DCI | 403 | 24 months | GBP | 28,175* (26,773) | – | 41,293 (39,239) | – |
| No DCI | 1199 | 24 months | 18,805 (17,287) | – | 27,561 (25,336) | – | |||
| Chotai et al. (2021) [42]b | 2012–2015 | VSP | 1001 | – | USD | – |
101,735.42** (69,372.66–145,622.18) |
– |
80,059 (54,591–114,595) |
| No VSP | 4351 | – | USD | – |
67,790.77 (46,150.95–105,320.71) |
– |
53,347 (36,318–82,880) |
||
| Chou et al. (2010) [43]c | 1999–2004 | TCD-defined VSP | 116 | – | USD | 134,135† (62,859) |
118,699 (47,258–418,687) |
119,028 (55,780) |
105,331 (41,936–371,533) |
| No TCD-defined VSP | 73 | – | USD | 106,246 (47,360) |
91,181 (38,447–293,845) |
94,280 (42,026) |
80,912 (34,117–260,751) |
||
| DCI | 62 | – | USD | 150,101† (59,156) |
141,571 (77,340–418,687) |
133,196 (52,494) |
125,627 (68,630–371,533) |
||
| No DCI | 127 | – | USD | 110,310 (54,285) |
91,181 (38,447–309,413) |
97,887 (48,171) |
80,912 (34,117–274,566) |
||
| Yundt et al. (1996) [64]d | 1993–1994 | Surgically treated unruptured aneurysm | 28 | – | USD | 12,685 (8,783) | – | 22,233 (15,394) | – |
| aSAH | 42 | – | USD | 22,622 (20,897) | – | 39,650 (36,626) | – | ||
| SAH with VSP | 32 | – | USD | 38,415‡ (21,324) | – | 67,330 (37,375) | – | ||
| SAH negative angiogram | 10 | – | USD | 25,994 (33,475) | – | 45,560 (58,672) | – | ||
aSAH, aneurysmal subarachnoid hemorrhage; DCI, delayed cerebral infarction; GBP, British pound sterling; IQR, interquartile range; SAH, subarachnoid hemorrhage; SD, standard deviation; USD, US dollar; VSP, cerebral vasospasm
*p < 0.05 versus no DCI; **p < 0.001 versus no VSP; †p < 0.05 versus no VSP; ‡p < 0.001 versus surgically treated unruptured intracerebral aneurysm
aTreatment = Unspecified. bTreatment = Mixed (coiling, clipping). cTreatment = Mixed (coiling, clipping). Unadjusted inpatient costs. dTreatment = Mixed (clipping, not specified)