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. 2022 Apr 28;13:871660. doi: 10.3389/fendo.2022.871660

Table 3.

ROC curves to determine cutoff values of each indicator for withdrawal from insulin therapy.

Parameter AUC p value Cut-off Sensitivity Specificity Odd ratios
Fasting blood glucose (mg/dL) 0.60675 n.s 141.0 80.0 55.6 0.997
Fasting C-peptide (ng/mL) 0.59167 n.s 1.00 85.7 36.1 1.299
Fasting C-peptide index 0.60873 n.s 0.56 100.0 25.0 1.753
Blood glucose after glucagon loading (mg/dL) 0.61746 n.s 155.0 77.1 58.3 0.996
C-peptide after glucagon loading (ng/mL) 0.66508 <0.05 2.30 77.1 58.3 1.486
C-peptide index after glucagon loading 0.69286 <0.05 1.25 91.4 52.8 2.152
ΔCPR (ng/mL) 0.70476 <0.05 1.00 77.1 66.7 2.888
HOMA-β (%) 0.64315 n.s 14.8 84.4 54.8 1.023
SUIT 0.63810 n.s 25.6 77.1 55.6 1.012
24-hour urine C-peptide (μg/day) 0.54167 n.s 35.6 65.7 58.3 0.999

ΔCPR, delta C-peptide; HOMA-β, homeostatic model assessment beta cell function; SUIT, secretory unit of islet transplantation.

NS, Not Significant.