Table 3.
ROC curves to determine cutoff values of each indicator for withdrawal from insulin therapy.
Parameter | AUC | p value | Cut-off | Sensitivity | Specificity | Odd ratios |
---|---|---|---|---|---|---|
Fasting blood glucose (mg/dL) | 0.60675 | n.s | 141.0 | 80.0 | 55.6 | 0.997 |
Fasting C-peptide (ng/mL) | 0.59167 | n.s | 1.00 | 85.7 | 36.1 | 1.299 |
Fasting C-peptide index | 0.60873 | n.s | 0.56 | 100.0 | 25.0 | 1.753 |
Blood glucose after glucagon loading (mg/dL) | 0.61746 | n.s | 155.0 | 77.1 | 58.3 | 0.996 |
C-peptide after glucagon loading (ng/mL) | 0.66508 | <0.05 | 2.30 | 77.1 | 58.3 | 1.486 |
C-peptide index after glucagon loading | 0.69286 | <0.05 | 1.25 | 91.4 | 52.8 | 2.152 |
ΔCPR (ng/mL) | 0.70476 | <0.05 | 1.00 | 77.1 | 66.7 | 2.888 |
HOMA-β (%) | 0.64315 | n.s | 14.8 | 84.4 | 54.8 | 1.023 |
SUIT | 0.63810 | n.s | 25.6 | 77.1 | 55.6 | 1.012 |
24-hour urine C-peptide (μg/day) | 0.54167 | n.s | 35.6 | 65.7 | 58.3 | 0.999 |
ΔCPR, delta C-peptide; HOMA-β, homeostatic model assessment beta cell function; SUIT, secretory unit of islet transplantation.
NS, Not Significant.