TABLE 4.

The largest nine clusters in the reference co-citation network.

Cluster	Size	Mean silhouette	Mean year	Label (LLR algorithm)	Representative Reference
0	72	0.995	2015	Heart failure	Tang et al. (15)
1	60	0.949	2008	High fat diet	Cani et al. (18)
2	32	1	2010	Infection	Sohail et al. (19)
3	19	0.988	2004	Gut	Sandek et al. (20)
4	18	1	2010	Cholesterol	Parnell et al. (21)
5	16	1	2011	Procalcitonin	Schuetz et al. (22)
7	12	1	2008	Infective endocarditis	Habib et al. (23)
10	7	1	2012	Inulin	Everard et al. (24)
18	3	0.987	2011	Light-intensity training	Turnbaugh et al. (25)

“Size” means the number of references that a cluster contains. “LLR” means log-likelihood ratio.