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. 2022 Apr 28;13:893137. doi: 10.3389/fimmu.2022.893137

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Copyright © 2022 Albakova, Mangasarova, Albakov, Nikulina, Kravchenko and Sapozhnikov

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of anti-PD-1 treatment on HSP90 expression in peripheral blood lymphocytes in r/r cHL patients. (A) Frequencies of T, B, NK and NKT cells following 24hr treatment with Nivolumab in r/r cHL patients (n=3). (B) Representative histogram showing increase in NK cell frequency after 24hr treatment with Nivolumab. iHSP90β expression (C) and sHSP90β (D), iTRAP1 (E) and sTRAP1 (F), iSTIP1 (G) and sSTIP1 (H) in peripheral blood lymphocytes of r/r cHL patients at 24 hrs treatment with Nivolumab (n=3). ns, not significant, *p<0.05, **p< 0.01.