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. Author manuscript; available in PMC: 2022 May 12.
Published in final edited form as: Lancet Microbe. 2022 Mar 24;3(5):e376–e381. doi: 10.1016/S2666-5247(22)00034-9

Figure: Penicillin (A) and tetracycline (B) MICs in isolates with susceptibility-associated genotypes, global and validation datasets.

Figure:

Dashed lines indicate Clinical & Laboratory Standards Institute breakpoints for susceptibility and resistance. (A) Penicillin MICs of isolates with penA_101 and without blaTEM (susceptible genotype) compared with isolates with one or more of these determinants (non-susceptible genotypes). (B) Tetracycline MICs of isolates with wildtype rpsJ (57V) and without tetM (susceptible genotype) compared with isolates with one or more of these determinants (non-susceptible genotypes). MIC=minimum inhibitory concentration.