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. 2022 Apr 28;13:831357. doi: 10.3389/fneur.2022.831357

Table 1.

Demographic and clinical variables of fatigued and non-fatigue young stroke patients.

Whole group (n = 135) Fatigue (n = 50) Non-fatigue (n = 85) P-value
Age at index event, mean (sd) 39.0 (8.2) 39.5 (8.4) 38.8 (8.1) 0.62
Follow-up duration, mean (sd) 11.01 (8.0) 9.26 (8.0) 12.05 (7.8) 0.05
Male, n (%) 60 (44.4) 18 (36.0) 42 (49.4) 0.13
Education level (range) 4.71 (6) 4.58 (6) 4.79 (5) 0.35
Stroke type, n (%)
• TIA 12 (8.9) 4 (8.0) 8 (9.4) 0.78
• Ischemic stroke 123 (91.1) 46 (92.0) 77 (90.6)
NIHSS at admission, mean (sd) 6 (5) 6 (5) 6 (5) 0.79
CIS20-R fatigue score at follow-up, mean (sd) 30.3 (13.3) 44.8 (6.3) 21.8 (7.9) <0.001
Recurrent stroke, n (%) 24 (17.8) 13 (26.0) 11 (12.9) 0.05
mRS score at follow-up, mean (sd) 1.24 (0.9) 1.50 (1.02) 1.09 (0.7) 0.01
Depression at follow-up, n (%) 20 (14.8) 16 (32.0) 4 (4.7) <0.001
Anxiety at follow-up, n (%) 25 (18.5) 21 (42.0) 4 (4.7) <0.001

sd, standard deviation; TIA, transient ischemic attack; NIHSS, National Institutes of Health Stroke Scale; CIS, Checklist Individual Strength; mRS, modified Rankin Scale. Bold indicates significant P-values (P < 0.05).