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. 2022 Apr 28;12:848341. doi: 10.3389/fonc.2022.848341

Figure 2.

Figure 2

The sorting and secretion mechanisms of circRNA in exosomes (A) lncRNAs competitively regulate circRNAs sorting into exosomes. (B) circRNAs act as miRNA sponges. (C) RBPs recognize RNA with specific binding sequences and regulate the sorting of exosomal circRNAs. (D) Exosomes preferentially release smaller circRNAs.