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. 2022 Apr 28;12:870820. doi: 10.3389/fonc.2022.870820

Figure 4.

Figure 4

Schematic illustration of the molecular and cellular events triggered by the N-cadherin switch at EMT. Overexpressed N-cadherin binds and stabilizes FGFR on the cell surface to initiate cell signalling cascades, and to PDGFR to increase cell motility through interactions with ß-catenin.