Table 2.
Comparison of D-Dimer, PAI-1, TAT, and F1 + 2 Levels in the VTE + and VTE- Subgroups.
| T1 | T2 | T3 | T4 | |||||
|---|---|---|---|---|---|---|---|---|
| VTE | VTE + | VTE- | VTE + | VTE- | VTE + | VTE- | VTE + | VTE- |
| D-dimer (ug/mL) | ||||||||
| Mean (± SD) | 0.76 ± 0.78 | 0.68 ± 0.95 | 7.9 ± 8.18 | 7.16 ± 9.08 | 6.48 ± 3.66 | 5.78 ± 5.29 | 2.94 ± 1.59 | 2.37 ± 1.53 |
| P value† | 0.54 | 0.56 | 0.34 | 0.01 | ||||
| PAI-1 (ng/mL) | ||||||||
| Mean (± SD) | 23.33 ± 7.61 | 25.73 ± 12.57 | 25.44 ± 9.14 | 24.54 ± 13.15 | 37.05 ± 14.47 | 25.13 ± 8.81 | 25.56 ± 10.09 | 22.77 ± 8.87 |
| P value† | 0.15 | 0.61 | < 0.001 | 0.04 | ||||
| TAT (ng/mL) | ||||||||
| Mean (± SD) | 13.9 ± 10.13 | 13.57 ± 11.93 | 14.42 ± 14.15 | 14.09 ± 13.85 | 23.67 ± 10.33 | 16.78 ± 11.92 | 20.07 ± 17.06 | 12.55 ± 18.76 |
| P value† | 0.84 | 0.87 | < 0.001 | 0.005 | ||||
| F1 + 2 (ng/mL) | ||||||||
| Mean (± SD) | 8.93 ± 5.11 | 8.51 ± 4.52 | 8.99 ± 5.16 | 8.87 ± 4.64 | 13.75 ± 4.9 | 9.05 ± 4.54 | 19.45 ± 4.78 | 9.55 ± 4.60 |
| P value† | 0.54 | 0.86 | < 0.001 | < 0.001 | ||||
PAI-1, plasminogen activator inhibitor-1; TAT, thrombin–antithrombin; F1 + 2, prothrombin fragment F1 + 2; VTE, venous thromboembolism; T1, preoperative 1-3 days; T2, 2 hours after surgery; T3, postoperative day 1; T4, postoperative day 3. † Using Student t test.