Table 4.
Overall effect | Heterogeneity | Egger's test | Overall effect | Heterogeneity | Egger's test | Overall effect | Heterogeneity | Egger's test | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SMD | p -value | I 2 | Q (P) | SMD | p -value | I 2 | Q (P) | SMD | p -value | I 2 | Q (P) | ||||
AD vs. Controls | MCI vs. Controls | AD vs. MCI | |||||||||||||
FAZ | 0.54 [0.09, 0.99] | 0.02 | 84.1% | <0.001 | 0.0002 | 0.27 [−0.03, 0.57] | 0.08 | 58.2% | 0.04 | 0.848 | −0.07 [−0.32, 0.18] | 0.59 | 0.0% | 0.69 | 0.651 |
Choroidal thickness | −0.58 [−1.26, 0.10] | 0.09 | 88.4% | <0.001 | 0.436 | - | - | - | - | - | - | - | - | - | - |
SCP vessel density | |||||||||||||||
Mean | −0.48 [−0.70, −0.27] | <0.001 | 48.2% | 0.04 | 0.227 | −0.42 [−0.81, −0.03] | 0.03 | 79.3% | <0.001 | 0.705 | −0.29 [−0.64, 0.07] | 0.12 | 59.3% | 0.04 | 0.145 |
Fovea | −0.38 [−0.66, −0.10] | 0.01 | 36.6% | 0.19 | 0.025 | −0.36 [−0.65, −0.07] | 0.02 | 20.7% | 0.26 | 0.573 | 0.04 [−0.61, 0.68] | 0.91 | 75.5% | 0.04 | - |
Parafovea | −0.48 [−0.71, −0.25] | <0.001 | 41.6% | 0.10 | 0.217 | −0.37 [−0.95, 0.21] | 0.21 | 83.1% | <0.001 | 0.528 | −0.31 [−0.82, 0.20] | 0.23 | 74.4% | 0.01 | 0.119 |
DCP vessel density | −1.19 [−2.00, −0.38] | <0.001 | 92.4% | <0.001 | 0.002 | −0.53 [−0.85, −0.22] | <0.001 | 59.7% | 0.02 | 0.968 | −0.68 [−1.37, 0.01] | 0.05 | 84.1% | <0.001 | 0.206 |
Peripapillary vessel density | −0.17 [−0.66, 0.31] | 0.49 | 70.5% | 0.04 | 0.221 | −0.43 [−0.73, −0.14] | <0.001 | 0.0% | 0.53 | 0.268 | - | - | - | - | - |
Choroidal perfusion density | −0.01 [−0.22, 0.20] | 0.91 | 0.0% | 0.73 | 0.719 | −0.27 [−0.80, 0.26] | 0.31 | 61.3% | 0.11 | – | 0.24 [−0.29, 0.77] | 0.37 | 48.2% | 0.16 | – |
SCP, Superficial capillary plexus; DCP, Deep capillary plexus; FAZ, Foveal avascular zone.