Fig. 6.

Development and orthopedic applications of silicon-doped POC-based biomaterials. (A) Synthesis schematic of CMSPC elastomers; (B) Mechanical properties of CMSPC hybrid elastomers; (C) Osteogenic differentiation of MC3T3-E1 cells after culture with CMSPC elastomers [85]; Copyright 2015, John Wiley and Sons. (D) Synthesis schematic of POC-POSS elastomers; (E) Calcium deposition mineralization on different elastomers with cells (left) and without cells (right) [86]; Copyright 2016, American Chemical Society. (F) Synthesis schematic of PCS-BGN elastomers; (G) Osteoblastic genes expressions of MC3T3-E1 after culture with PCS−BGN elastomers [89]; Copyright 2018, American Chemical Society. (H) Schematic diagram of PPM nanofibrous scaffold to recover bone tissue defect; (I) Micro-CT images of new bone formation in rat calvarial defect model; (J) Bone formation from the defect in 6 weeks [91]. Copyright 2019, John Wiley and Sons. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)