Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr;10(8):435. doi: 10.21037/atm-21-5699

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

Heat mapping showing the semi-quantitative analysis of CLS in inguinal (subcutaneous WAT) and epididymal (visceral WAT) adipose tissue. (A) Colors vary in shades of blue, with an intensity proportional to the number of CLS in the respective adipose tissue. The evaluations were performed by an examiner blinded to the experimental groups. After the analysis, one representative picture per group was selected to compose the panel of representative images. Images were captured using a Zeiss AxioImager M2 light microscope under ×200 magnification (Carl Zeiss, Gottingen, Germany). Representative histological images of inguinal adipose tissue in: water control group (water + saline; B), NTG-injected rats (water + NTG; C), rats with n-3 supplementation (water + n-3; D), NTG-injected rats with n-3 supplementation (water + n-3 + NTG; E), HFD control group (HFD + saline; F), HFD NTG-injected rats (HFD + NTG; G), HFD rats with n-3 supplementation (HFD + n-3; H), and HFD NTG-injected rats with n-3 supplementation (HFD + n-3 + NTG; I), respectively; and epididymal adipose tissue in: water control group (water + saline; J), NTG-injected rats (water + NTG; K), rats with n-3 supplementation (water + n-3; L), NTG-injected rats with n-3 supplementation (water + n-3 + NTG; M), HFD control group (HFD + saline; N), HFD NTG-injected rats (HFD + NTG; O), HFD rats with n-3 supplementation (HFD + n-3; P), and HFD NTG-injected rats with n-3 supplementation (HFD + n-3 + NTG; Q), respectively. The red asterisks indicate the adipocytes presenting CLS. CLS, crown-like structure. WAT, white adipose tissues; NTG, nitroglycerin; HFD, high fructose diet.