Table 1. Body weight and body weight variation from days 1 to 30, 30 to 45 and 45 to 60 in water control group (water + saline), HFD control group rats (HFD + saline), NTG-injected rats (water + NTG), and HFD NTG-injected rats (HFD + NTG), with or without n-3 supplementation (water + n-3; HFD + n-3; n-3 + NTG; HFD + n-3 + NTG).
Body weight evaluation | Water | HFD | |||||||
---|---|---|---|---|---|---|---|---|---|
Saline | NTG | n-3 | n-3 + NTG | Saline | NTG | n-3 | n-3 + NTG | ||
BW mean days 1–30 (g) | 294.0±16.0 | – | – | – | 303.0±17.0 | – | – | – | |
BW mean days 30–45 (g) | 403.6±6.5a | – | 401.0±6.4j | – | 425.0±8.0a | – | 426.0±8.0j | – | |
BW mean days 45–60 (g) | 439.4±3.5a,b | 429.0±3.0b,k | 438.0±4.0j | 426.4±4.0l | 455.5±4.0a,f | 475.0±2.0f,i,k | 467.0±4.0j | 458.0±3.0l,i | |
ΔBW days 1–30 (g) | 176.0±4.0a | – | – | – | 190±4.5a | – | – | – | |
ΔBW days 30–45 (g) | 41.4±2.0a | – | 39.5±3.0j | – | 54.4±2.0a | – | 52.0±3.0j | – | |
ΔBW days 45–60 (g) | 26.0±2.5b | −9.2±7.0b | 29.0±3.0d | −21.0±10.0 d | 30.0±2.4f | 3.4±5.0f | 29.0±3.0h | –12.6±9.0h | |
ΔBW days 1–60 (g) | 246.5±12.0 | 229.0±11.4 (P=0.05) | 254.0±6.7 | 217.8±17.6 | 264.1±7.9 | 283.0±11.0 (P=0.05) | 273.4±14.7 | 251.5±14.3 |
Data are presented as means ± SEM of 10 to 12 rats per group for body weight (two-way ANOVA followed by Tukey’s post hoc test; one-way ANOVA followed by uncorrected Fisher’s LSD’s post hoc; or Kruskal-Wallis followed by uncorrected Dunn’s post hoc test). a, P<0.05 water + saline vs. HFD + saline; b, P<0.05 water + saline vs. water + NTG; d, P<0.05 water + n-3 vs. water + n-3 + NTG; f, P<0.05 HFD + saline vs. HFD + NTG; h, P<0.05 HFD + n-3 vs. HFD + n-3 + NTG; i, P<0.05 HFD + NTG vs. HFD + n-3+ NTG; j, P<0.05 water + n-3 vs. HFD + n-3; k, P<0.05 water + NTG vs. HFD + NTG; l, P<0.05 water + n-3 + NTG vs. HFD + n-3+ NTG. BW, body weight; NTG, nitroglycerin; HFD, high fructose diet; SEM, standard error of the mean.