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. 2022 Apr;10(8):439. doi: 10.21037/atm-21-4636

Figure 4.

Figure 4

Fraxetin alleviates ischemic brain injury in mice. (A) Representative TTC staining images at day 3 after MCAO; (B) quantification of TTC staining (n=8); (C-E) mNSS score (C), grip strength (D), and a rotarod test (E) were used to detect neurological deficits after MCAO. Saline group n=10, fraxetin group n=12. The values represent mean ± SEM. *P<0.05, **P<0.01, ***P<0.001 vs. MCAO-saline group. TTC, 2,3,5-triphenyltetrazolium chloride; MCAO, middle cerebral artery occlusion; mNSS, modified neurological severity score; SEM, standard error of the mean.