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. 2022 Apr;10(8):473. doi: 10.21037/atm-22-945

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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TCGA database analysis of the significance of CRNDE expression in ATC tissues. (A) The TCGA database showed that CRNDE was highly expressed in THCA tissue compared to normal thyroid tissue. (B) Logistic regression analysis showed that CRNDE played a critical role in the diagnosis of THCA. (C) Both GSE33630 and GSE29265 datasets showed that CRNDE was specifically and highly expressed in ATC tissues. CRNDE, colorectal neoplasia differentially expressed; TCGA, The Cancer Genome Atlas; PTC, papillary thyroid carcinoma; ATC, anaplastic thyroid cancer; THCA, thyroid cancer.