Figure 1.
Preferred Reporting Items for Systematic Reviews and Meta-Analyses diagram of the study selection. Diagram provides details on the selection process of studies for inclusion. Note that the exclusion of 2703 citations at the ‘screening’ stage did not meet our study inclusion/exclusion criteria based on screening of title/abstract. CDC, Centers for Disease Control and Prevention; DISCOVER, study by Mayer et al.;28 FEM-PrEP, study by Van Damme et al.;7 HPTN 067/ADAPT, study by Bekker et al;24 IPERGAY, study by Molina et al.;5 iPrEX, study by Grant et al;3 OLE, open label extension; PrEP, pre-exposure prophylaxis; PROUD, study by McCormack et al.;6 RCT, randomised controlled trial.