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. 2022 May 4;2022:8169981. doi: 10.1155/2022/8169981

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Copyright © 2022 Kexin Kang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Differential expression analysis. (a) IGF1 expression between AD and non-dementia controls in GSE132903. Volcano plots of DEGs in AD/control (b) and IGF1-low/high (c) groups: blue and red represent down-regulated and up-regulated, respectively. (d) Clustering heatmap of the top 50 down- and up-regulated DEGs between AD and non-dementia controls: the gradual change of color from green to red indicates that the gene expression changes from down-regulation to up-regulation. AD: Alzheimer's disease; DEGs: differentially expressed genes.