Fig. 5.

Examples of solid and lost footing for evaluation of ledge test. (A) Example of mouse with solid hindlimb footing during the ledge test where limbs are consistently placed high and near the cage edge, which receives a score of 0. (B) A mouse who has lost footing, or slips, during the ledge test will display feet below the cage edge. Slips occur when one, but not both, hindlimbs are on the side of the ledge. Lost footing is occasionally seen in a ledge score of 0 and is consistently seen in ledge score of 1. (C) A mouse with both hindlimbs hugging the sides of the cage and using them less or ineffectively would receive a score of 2 or 3, respectively. (D) A mouse that is unable to remain centered on the ledge which causes its hind end and hindlimbs to slip sideways off the ledge receives a score of 3.