Table 1.
Baseline Characteristics of the Participants.*
| Characteristic | Endocrine-Only Group (N = 2507) | Chemoendocrine Group (N = 2511) | All Participants (N = 5018) |
|---|---|---|---|
| Median age (range) — yr | 57.2 (18.3–86.0) | 57.9 (28.0 −87.6) | 57.5 (18.3–87.6) |
| Age category — no. (%) | |||
| <40 yr | 80 (3.2) | 67 (2.7) | 147 (2.9) |
| 40–49 yr | 547 (21.8) | 530 (21.1) | 1077 (21.5) |
| 40–49 yr | 547 (21.8) | 530 (21.1) | 1077 (21.5) |
| 50–59 yr | 838 (33.4) | 837 (33.3) | 1675 (33.4) |
| 60–69 yr | 761 (30.4) | 777 (30.9) | 1538 (30.6) |
| ≥70 yr | 281 (11.2) | 300 (12.0) | 581 (11.6) |
| Menopausal status — no. (%) | |||
| Premenopausal | 831 (33.1) | 834 (33.2) | 1665 (33.2) |
| Postmenopausal | 1676 (66.9) | 1677 (66.8) | 3353 (66.8) |
| Recurrence score — no. (%)† | |||
| 0–13 | 1071 (42.7) | 1076 (42.9) | 2147 (42.8) |
| 14–25 | 1436 (57.3) | 1435 (57.1) | 2871 (57.2) |
| Axillary surgery — no. (%) | |||
| Axillary lymph-node dissection, with or without sentinel-node mapping | 1571 (62.7) | 1569 (62.5) | 3140 (62.6) |
| Sentinel-node biopsy without axillary lymph-node dissection | 936 (37.3) | 942 (37.5) | 1878 (37.4) |
| Positive nodes — no. (%) | |||
| 1 node | 1647 (65.7) | 1628 (64.8) | 3275 (65.3) |
| 2 nodes | 623 (24.8) | 643 (25.6) | 1266 (25.2) |
| 3 nodes | 229 (9.1) | 231 (9.2) | 460 (9.2) |
| Not reported | 8 (0.3) | 9 (0.4) | 17 (0.3) |
*
Percentages may not total 100 because of rounding.
†
The recurrence score based on the 21-gene breast-cancer assay ranges from 0 to 100, with higher scores indicating a worse prognosis.