FIG. 2.

Inhibition of the bactericidal activities of pediocin-like bacteriocins due to the presence of 5 μM peptide fragments derived from pediocin PA-1. Inhibition of the bactericidal activities is quantitated as the increase in MIC due to the presence of a fragment. The increase in MIC is defined as the MIC obtained in the presence of a fragment divided by the MIC obtained in the absence of a fragment. The MICs were between 0.5 and 0.05 nM for all of the bacteriocins in the absence of a fragment, with sakacin P having the highest MIC, enterocin A the lowest, and curvacin A, pediocin PA-1, and leucocin A having MICs between those of sakacin P and enterocin A.