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KMUP-1 attenuates c-Fos and nuclear NFATc1 expression induced by PgLPS in RANKL-primed pre-osteoclasts. The expression of (A,B) c-Fos and (C,D) nuclear NFATc1was analyzed in RANKL-primed RAW 264.7 cells 24 h after PgLPS stimulation using western blot assay. Lamin B2 or β-Actin was used as an internal control. n = 5. ##p < 0.01, ###p < 0.001 compared with control; *p < 0.05, **p < 0.01, ***p < 0.001 compared with PgLPS.
