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. 2022 Apr 28;7(18):16055–16062. doi: 10.1021/acsomega.2c01316

Table 2. Minimum Inhibitory Concentration (MIC in μg/mL) of Synthesized 9ak Compounds against the Selected Penal of Microbial Agentsa.

  Gram-negative bacteria
Gram-positive bacteria
Fungi
compound E. coli K. pneumonia P. aeruginosa S. aureus B. subtilis P. fluorescens S. pyogenes A. janus A. niger A. sclerotiorum F. oxysporum P. glabrum
9a 32 32 32 32 16 32
9b 4 8 16 4 4 8 16 8 4 16 8 4
9c 8   16 32 16 16 32 32 16 16
9d 4 4 8 4 8 16 16 4 8 8 4 8
9e 8 32 32 8 16 16 16 32 32 16
9f 4 8 16 8 8 4 8 16 8 16 8 8
9g 16 16 16 8 32 16 16 16
9h 32 32 32 32 32
9i 16 8 16 16 8 32 16 32 16
9j 32 16 32 8 32
9k 16 16 8 16 16 8 8 8 4 4
Amoxicillin 4 4 4 4 4 4 4
Fluconazole 2 2 2 2 2
a

Where “–” indicates no antimicrobial activity.