Table 2. Minimum Inhibitory Concentration (MIC in μg/mL) of Synthesized 9a–k Compounds against the Selected Penal of Microbial Agentsa.
Gram-negative
bacteria |
Gram-positive
bacteria |
Fungi |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
compound | E. coli | K. pneumonia | P. aeruginosa | S. aureus | B. subtilis | P. fluorescens | S. pyogenes | A. janus | A. niger | A. sclerotiorum | F. oxysporum | P. glabrum |
9a | – | – | – | 32 | 32 | – | 32 | 32 | 16 | – | 32 | – |
9b | 4 | 8 | 16 | 4 | 4 | 8 | 16 | 8 | 4 | 16 | 8 | 4 |
9c | 8 | 16 | 32 | 16 | 16 | 32 | 32 | 16 | 16 | – | – | |
9d | 4 | 4 | 8 | 4 | 8 | 16 | 16 | 4 | 8 | 8 | 4 | 8 |
9e | 8 | 32 | 32 | 8 | 16 | 16 | 16 | 32 | – | – | 32 | 16 |
9f | 4 | 8 | 16 | 8 | 8 | 4 | 8 | 16 | 8 | 16 | 8 | 8 |
9g | 16 | 16 | – | 16 | 8 | 32 | 16 | 16 | 16 | – | – | – |
9h | – | 32 | 32 | – | 32 | – | – | – | 32 | 32 | – | – |
9i | 16 | 8 | – | 16 | 16 | 8 | – | 32 | 16 | 32 | 16 | – |
9j | 32 | – | – | 16 | 32 | – | – | – | 8 | – | – | 32 |
9k | 16 | 16 | – | 8 | 16 | – | 16 | 8 | 8 | 8 | 4 | 4 |
Amoxicillin | 4 | 4 | 4 | 4 | 4 | 4 | 4 | – | – | – | – | – |
Fluconazole | – | – | – | – | – | – | – | 2 | 2 | 2 | 2 | 2 |
Where “–” indicates no antimicrobial activity.