Table 2.
Complete blood count and biochemistry panel performed in a 14-year-old dog suffering from bilateral hip and elbow osteoarthritis and severe neck pain, before and after liposomal cannabidiol subcutaneous injection.
| Parameter | Reference range | Baseline-10 days | 3 days | 2 weeks | 4 weeks |
|---|---|---|---|---|---|
| Hematology | |||||
| White blood cells (109/L) | 5.0–22.0 | 8.98 | 14.32 | 8.18 | 5.88 |
| Neutrophils (109/L) | 2.0–12.8 | 7.52 | 12.29 | 6.41 | 5.05 |
| Lymphocytes (109/L) | 0.6–12.8 | 0.89 | 1.16 | 0.83 | 0.49 L |
| Monocytes (109/L) | 0.0–2.8 | 0.52 | 0.84 | 0.83 | 0.33 |
| Eosinophils (109/L) | 0.0–2.0 | 0.04 | 0.03 | 0.07 | 0.01 |
| Basophils (109/L) | 0.0–0.5 | 0.00 | 0.01 | 0.03 | 0.00 |
| Neutrophils (%) | 50.0–80.0 | 83.76 H | 85.79 H | 78.41 | 85.96 H |
| Lymphocytes (%) | 12.0–30.0 | 9.91 L | 8.11 L | 10.20 L | 8.31 L |
| Monocytes (%) | 0.0–14.0 | 5.83 | 5.85 | 10.14 | 5.55 |
| Eosinophils (%) | 0.0–10.0 | 0.45 | 0.20 | 0.90 | 0.14 |
| Basophils (%) | 0.0–2.5 | 0.05 | 0.04 | 0.36 | 0.04 |
| Hematocrit (%) | 35.8–60.0 | 31.6 L | 27.6 L | 26.8 L | 34.2 L |
| Red blood cells (1012/L) | 4.35–9.20 | 4.34 L | 3.50 L | 3.67 L | 4.65 |
| Hemoglobin (g/dL) | 11.0–19.5 | 10.1 L | 8.1 L | 9.6 L | 10.8 L |
| Mean corpuscular volume (fL) | 60.0–80.0 | 72.7 | 79.0 | 73.1 | 73.6 |
| Mean corpuscular hemoglobin (pg) | 19.0–24.5 | 23.3 | 23.1 | 26.2 H | 23.2 |
| Mean corpuscular hemoglobin concentration (g/dL) | 30.0–36.0 | 32.0 | 29.3 L | 35.8 | 31.6 |
| Red cell distribution width (%) | 10.5–18.0 | 13.2 | 16.4 | 13.7 | 13.3 |
| Reticulocytes (109/L) | 0.0–60.0 | 59.5 | 140.4 H | 40.4 | 39.1 |
| Reticulocytes (%) | 0.0–1.2 | 1.37 H | 4.01 H | 1.10 | 0.84 |
| Platelets (109/L) | 200–500 | 351 | 518 H | 427 | 467 |
| Plateletcrit (%) | 0.435 | 0.611 | 0.474 | 0.542 | |
| Mean platelet volume (fL) | 6.0–17.0 | 12.4 | 11.8 | 11.1 | 11.6 |
| Platelets distribution width (%) | 24.9 | 25.1 | 26.5 | 25.1 | |
| Packed Cell Volume (%) | 31 | 25 | 30 | 33 | |
| Total solids | 6.4 | 7.0 | 6.4 | 6.4 | |
| Biochemistry | |||||
| Albumin (g/dL) | 2.5–4.4 | 3.3 | 3.2 | 3.1 | 3.2 |
| Alkaline phosphatase (U/L) | 20–150 | 47 | 66 | 54 | 50 |
| Alanine transaminase (U/L) | 10–118 | 24 | 22 | 29 | 43 |
| Amylase (U/L) | 200–1,200 | 559 | 714 | 493 | 469 |
| Total bilirubin (mg/dL) | 0.1–0.6 | 0.3 | 0.4 | 0.3 | 0.3 |
| Blood urea nitrogen (mg/dL) | 7–25 | 11 | 17 | 12 | 11 |
| Calcium (mg/dL) | 8.6–11.8 | 9.3 | 9.3 | 9.1 | 9.1 |
| Phosphorus (mg/dL) | 2.9–6.6 | 3.0 | 4.3 | 5.5 | 5.7 |
| Creatinine (mg/dL) | 0.3–1.4 | 0.7 | 0.9 | 0.6 | 0.8 |
| Glucose (mg/dL) | 60–110 | 127 | 93 | 97 | 107 |
| Sodium (mmol/dL) | 138–160 | 145 | 147 | 146 | 146 |
| Potassium (mmol/dL) | 3.7–5.8 | 3.4 | 4.1 | 4.7 | 4.2 |
| Total protein (g/dL) | 5.4–8.2 | 6.2 | 6.8 | 6.4 | 6.6 |
| Globulins (g/dL) | 2.3–5.2 | 2.8 | 3.6 | 3.3 | 3.3 |
High (H) or low (L) relative to the “Reference range” values column for healthy dogs.