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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: J Am Coll Cardiol. 2022 May 10;79(18):1858–1869. doi: 10.1016/j.jacc.2022.02.050

Figure 4. Stressed and unstressed volume in HFpEF, obesity phenotype.

Figure 4.

A. Comparison of total blood volume, stressed blood volume (SBV) and unstressed blood volume (UBV) at rest and during exercise in controls and patients with HFpEF. B. Explanation of why, despite a greater increase of SBV during exercise in HFpEF patients, they have a markedly blunted increase of cardiac output. C. Relationship between percent of blood ascribed to SBV as a function of body mass index (BMI). Adapted from (32).