Table 1.
HR1a |
HR2b |
|||||
---|---|---|---|---|---|---|
Positive reference PAP | Negative reference PAP | Total | Positive reference PAP | Negative reference PAP | Total | |
Positive mPAP | 4 | 0 | 4 | 12 | 1 | 13 |
Negative mPAP | 4 | 135 | 139 | 25 | 105 | 130 |
Total | 8 | 135 | 143 | 37 | 106 | 143 |
HR1 definition of heteroresistance: growth of a resistant subpopulation of cells at 4 and 8 mg/L of colistin at a frequency of at least 1 × 10−6 the main population grown on antibiotic-free media.
HR2 definition of heteroresistance: growth of a resistant subpopulation of cells at a colistin concentration ≥8× higher than the main population, at a frequency of at least 1 × 10−7.