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. 2022 Apr 28;12:855101. doi: 10.3389/fonc.2022.855101

Table 3.

Sensitivity analyses to assess the robustness of the association between DRRD score and lung cancer.

Excluding participants Number of cases Person-years Adjusted HR (95%CI)*
Primary analysis 0 1632 866776.8 0.85 (0.73,0.98)
Excluding participants with extreme energy intake 1414 1594 854674.8 0.86 (0.74,0.99)
Excluding participants with extreme BMI 1930 1600 850434.9 0.85 (0.73,0.98)
Excluding participants with diabetes 6568 1519 812654.8 0.85 (0.74,0.99)
Excluding participants with a follow-up less than 2 years 1608 1336 865107.1 0.84 (0.72,0.99)

*Adjusted for age (continuous), sex (male or female), BMI (continuous), total energy intake (continuous), family history of lung cancer (yes, no, or possible), marital status (married or not married), race/ethnicity (white or non-white), smoking status (never, former smoker, current smoker), pack-years of cigarettes (continuous), alcohol intake (never, former, current, or unknown), history of diabetes (yes vs. no). Note: extreme energy intake was defined as >4000 kcal/day or <500 kcal/day; extreme BMI was defined as top 1% or bottom 1% in the included population.