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. 2022 Apr 28;13:829153. doi: 10.3389/fendo.2022.829153

Table 3.

The cycle characteristics and reproductive outcomes of ART in BPES patients with and without FOXL2 mutations.

Characteristics Mutation group Nonmutation group P
N 12 5
Gn starting dosage (IU) 229.17 ± 54.18 172.50 ± 22.36 0.042
Gn duration (days) 15.08 ± 4.54 10.00 ± 1.73 0.014
Total dosage of Gn (IU) 4926.25 ± 2073.73 2002.50 ± 648.22 0.008
E2 on trigger day (pg/mL) 1553.63 ± 1067.67 2768.00 ± 1039.91 0.048
No. of follicles >14mm on trigger day 4.83 ± 3.97 14.60 ± 6.19 0.001
No. of retrieved oocytes 2.75 ± 1.91 12.40 ± 6.19 0.001
No. of metaphase II oocytes 0.5 (0,3) 6 (3,16) 0.006
Maturation rate, % (n/N) 51.52% (17/33) 70.97% (44/62) 0.060
No. of fertilized oocytes 1 (0,2) 6 (2,8.5) 0.019
Fertilization rate, % (n/N) 42.42% (14/33) 43.55% (27/62) 0.916
No. of day 3 good-quality embryos 0 (0,0) 4 (1.5,4.5) 0.001
Day 3 good-quality embryos rate, % (n/N) 21.43% (3/14) 59.26% (16/27) 0.021
No. of good-quality blastocysts 0 (0,1) 2 (0.5,4) 0.037
Good-quality blastocysts rate, % (n/N) 28.57% (4/14) 40.74% (11/27) 0.443
Cancellation rate, % (n/N) 36.84% (7/19) 0 (0/5) 0.272

Data are expressed as the mean ± standard deviation or median (interquartile range).