Table 2.
Study period | Pre-treatment | Treatment | Follow-up | |||
---|---|---|---|---|---|---|
Timepoint (weeks) | <− 2 | 0 | 6 | 12 | 24 | 36 |
Enrollment | ||||||
Informed consent | X | |||||
Eligibility assessment | X | |||||
Baseline variables | X | |||||
Allocation | X | |||||
Interventions | ||||||
CCFES | ◊------ | ------------- | ------◊ | |||
cNMES | ◊------ | ------------- | ------◊ | |||
TOT | ◊------ | ------------- | ------◊ | |||
Assessments | ||||||
End of Treatment Questionnaire | X | |||||
SIS – Hand Section | X | X | X | |||
Neuro-QOL UE Function | X | X | X | |||
Modified Ashworth Scale | X | X | X | X | X | |
UEFM | X | X | X | X | X | |
BBT | X | X | X | X | X | |
SULCS | X | X | X | X | X | |
ARAT | X | X | X | X | X | |
MEP excitability | X | X | X | |||
Ipsilateral MEP excitability | X | X | X | |||
Interhemispheric inhibition | X | X | X |
CCFES contralaterally controlled functional electrical stimulation, cNMES cyclic neuromuscular electrical stimulation, TOT task-oriented-training, SIS stroke impact scale, QOL quality of life, UE upper extremity, UEFM upper extremity Fugl-Meyer assessment, BBT box and blocks test, SULCS stroke upper limb capacity scale, ARAT action research arm test, MEP motor evoked potential