Fig. 6.

MiR-107 affects BC progression by regulating the expression of NEDD9 in vivo. Nude mice were subcutaneously inoculated with stably transfected MDA-MB-231 cells with miR-107 overexpression or silencing. After the tumours were observed, tumour volume and mouse body weight were measured every 4 days. a Diagram of subcutaneous tumour formation in nude mice. b Tumour growth curve. c, d Tumour volume of xenograft tumours in different groups. e, f Scoring analysis and representative immunohistochemical images of NEDD9 expression in xenograft tumours (scale bar = 50 μm). n = 5; ***p < 0.001, **p < 0.01, *p < 0.05