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. 2022 May 12;22:533. doi: 10.1186/s12885-022-09603-3

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — miR-107 contributes to the inhibition of breast cancer metastasis in an orthotopic breast cancer model. a Bioluminescence imaging was performed at 4 weeks after inoculation. b Statistics of the fluorescence intensity of lung metastases in nude mice. c Pulmonary metastatic nodules were observed using HE staining. Scale bar = 100 μm. d Number of pulmonary metastatic nodules in each group. e Proportion of lung metastasis area compared to total lung area in each group. NC, control group; miR-107-OE, miR-107 overexpression group; NC-OE, miR-107 empty group. n = 5; **p < 0.01