Table 7.

Acute and chronic gastrointestinal toxicity by dosimetric parameters

	CTCAE Grade 2 + acute diarrhea			CTCAE Grade 2 + chronic colitis
	Odds ratio	95% CI	P	Odds ratio	95% CI	P
Colon
V35	0.88	0.73–1.06	0.182	1.10	0.86–1.41	0.451
V25	1.14	0.93–1.40	0.202	0.82	0.60–1.13	0.224
V15	0.93	0.83–1.04	0.186	1.05	0.93–1.18	0.448
Peritoneum
V50.4	0.80	0.57–1.12	0.198	1.09	0.76–1.56	0.629
V40	1.62	0.97–2.71	0.068	0.93	0.63–1.36	0.698
V30	0.80	0.54–1.18	0.250	1.25	0.83–1.87	0.287
V25	0.99	0.83–1.17	0.892	1.02	0.89–1.16	0.792
Rectum
V50.4	1.01	0.92–1.11	0.863	0.97	0.87–1.08	0.576
V40	0.92	0.83–1.02	0.116	0.84	0.67–1.06	0.147
V30	1.15	1.10–1.30	0.030*	1.14	0.99–1.33	0.073

CTCAE common terminology criteria for adverse events, CI confidence interval, V_50.4, V₄₀, V₃₅, V₃₀, V₂₅, V₁₅ = volume receiving ≥ 50.4, ≥ 40, ≥ 35, ≥ 30, ≥ 25, ≥ 15 Gy, respectively

*Statistically significant