Skip to main content
. 2022 May 12;17:91. doi: 10.1186/s13014-022-02063-w

Table 8.

Dosimetric comparison of organs at risk (OARs) for the 3 treatment plans

3DCRT (n = 9) VMAT (n = 11) Tomotherapy (n = 10) P value
Colon dose (%)
V35 34.7 [23.9–66.1] 13.0 [7.0–29.3]* 10.6 [3.5–17.1]* 0.002
V25 50.3 [41.2–74.3] 30.0 [18.5–53.0]& 30.4 [10.8–37.4]* 0.020
V15 64.9 [51.2–81.0] 68.0 [52.0–73.2] 57.1 [33.8–80.6] 0.796
Peritoneum dose (%)
V50.4 35.8 [18.0–50.0] 3.6 [1.0–5.0]* 2.7 [0.5–5.2]* 0.001
V40 51.7 [28.0–73.0] 12.0 [7.0–21.0]* * 0.002
V30 58.7 [35.2–79.7] 27.0 [20.0–37.0]* 23.6 [17.5–34.6]* 0.013
V25 66.7 [32.5–83.0] 45.0 [33.7–52.0] 36.6 [30.4–45.5] 0.147
Rectum dose (%)
V50.4 24.4 [15.6,–52.6] 2.2 [0.0–13.4]* 5.3 [0.3–7.4]* 0.003
V40 97.5 [94.2–100.0] 37.0 [26.0–68.4]* 34.1 [26.2–40.6]* < 0.001
V30 97.5 [96.3–100.0] 86.5 [69.3–90.0] 56.4 [49.3–66.0]*§ < 0.001
Bladder dose (%)
V50.4 40.7 [31.2–46.7] 2.0 [1.0–14.0]* 5.7 [0.7–13.3]* 0.001
V40 100.0 [99.8–100.0] 28.0 [23.3–34.1]* 28.6 [21.3–46.1]* < 0.001
V30 100.0 [100.0–100.0] 59.5 [52.0–71.0]* 50.5 [43.2–73.6]* < 0.001
Bone marrow dose (%)
V50 27.8 [24.1–29.2] 4.0 [2.7–5.0]* 5.5 [3.0–8.1]* < 0.001
V40 44.0 [39.7–45.5] 16.0 [13.0–17.0]* 19.6 [16.9–23.0]* < 0.001
V30 58.9 [54.8–62.9] 37.0 [34.2–38.5]* 39.2 [38.0–45.8]* < 0.001
V20 88.8 [81.5–91.3] 70.0 [63.0–75.4]* 70.4 [67.1–73.3]* 0.002
V10 91.9 [84.4–95.6] 89.8 [87.0–94.0] 90.2 [87.1–92.7] 0.936

3DCRT three-dimensional conformal radiation therapy, VMAT volumetric modulated arc therapy, V50.4, V40, V35, V30, V25, V15 = volume receiving ≥ 50.4, ≥ 40, ≥ 35, ≥ 30, ≥ 25, ≥ 15 Gy, respectively

Differences were compared using the Kruskal–Wallis tests for continuous variables

Data are presented as the median [interquartile range]

*P < 0.05 versus 3DCRT in the Bonferroni post hoc test

§P < 0.05 versus VMAT in the Bonferroni post hoc test

&P = 0.09 versus 3DCRT in the Bonferroni post hoc