Table 8.
3DCRT (n = 9) | VMAT (n = 11) | Tomotherapy (n = 10) | P value | |
---|---|---|---|---|
Colon dose (%) | ||||
V35 | 34.7 [23.9–66.1] | 13.0 [7.0–29.3]* | 10.6 [3.5–17.1]* | 0.002 |
V25 | 50.3 [41.2–74.3] | 30.0 [18.5–53.0]& | 30.4 [10.8–37.4]* | 0.020 |
V15 | 64.9 [51.2–81.0] | 68.0 [52.0–73.2] | 57.1 [33.8–80.6] | 0.796 |
Peritoneum dose (%) | ||||
V50.4 | 35.8 [18.0–50.0] | 3.6 [1.0–5.0]* | 2.7 [0.5–5.2]* | 0.001 |
V40 | 51.7 [28.0–73.0] | 12.0 [7.0–21.0]* | * | 0.002 |
V30 | 58.7 [35.2–79.7] | 27.0 [20.0–37.0]* | 23.6 [17.5–34.6]* | 0.013 |
V25 | 66.7 [32.5–83.0] | 45.0 [33.7–52.0] | 36.6 [30.4–45.5] | 0.147 |
Rectum dose (%) | ||||
V50.4 | 24.4 [15.6,–52.6] | 2.2 [0.0–13.4]* | 5.3 [0.3–7.4]* | 0.003 |
V40 | 97.5 [94.2–100.0] | 37.0 [26.0–68.4]* | 34.1 [26.2–40.6]* | < 0.001 |
V30 | 97.5 [96.3–100.0] | 86.5 [69.3–90.0] | 56.4 [49.3–66.0]*§ | < 0.001 |
Bladder dose (%) | ||||
V50.4 | 40.7 [31.2–46.7] | 2.0 [1.0–14.0]* | 5.7 [0.7–13.3]* | 0.001 |
V40 | 100.0 [99.8–100.0] | 28.0 [23.3–34.1]* | 28.6 [21.3–46.1]* | < 0.001 |
V30 | 100.0 [100.0–100.0] | 59.5 [52.0–71.0]* | 50.5 [43.2–73.6]* | < 0.001 |
Bone marrow dose (%) | ||||
V50 | 27.8 [24.1–29.2] | 4.0 [2.7–5.0]* | 5.5 [3.0–8.1]* | < 0.001 |
V40 | 44.0 [39.7–45.5] | 16.0 [13.0–17.0]* | 19.6 [16.9–23.0]* | < 0.001 |
V30 | 58.9 [54.8–62.9] | 37.0 [34.2–38.5]* | 39.2 [38.0–45.8]* | < 0.001 |
V20 | 88.8 [81.5–91.3] | 70.0 [63.0–75.4]* | 70.4 [67.1–73.3]* | 0.002 |
V10 | 91.9 [84.4–95.6] | 89.8 [87.0–94.0] | 90.2 [87.1–92.7] | 0.936 |
3DCRT three-dimensional conformal radiation therapy, VMAT volumetric modulated arc therapy, V50.4, V40, V35, V30, V25, V15 = volume receiving ≥ 50.4, ≥ 40, ≥ 35, ≥ 30, ≥ 25, ≥ 15 Gy, respectively
Differences were compared using the Kruskal–Wallis tests for continuous variables
Data are presented as the median [interquartile range]
*P < 0.05 versus 3DCRT in the Bonferroni post hoc test
§P < 0.05 versus VMAT in the Bonferroni post hoc test
&P = 0.09 versus 3DCRT in the Bonferroni post hoc