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. 2022 May 12;22:184. doi: 10.1186/s12935-022-02576-0

Fig. 5.

Fig. 5

LINC00662 propels BC tumor growth and cell stemness. A Ten nude mice transplanted with subcutaneous xenografts were chosen as the vivo specimens. B Tumor growth curve was plotted to present tumor growth along with time. C, D Tumor weight and volume change was detected after knockdown of LINC00662. E Expression levels of stemness-related proteins were uncovered through western blot assay in BC tissues excised from mice. F Ki67 and cleaved caspase 3 were detected through IHC to evaluate the proliferation and apoptosis of BC tissues. GI Correlation analysis using R square graphs confirmed the correlation between LINC00662, miR-144-3p and SOX2 in vivo. ** p < 0.01