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. 2022 Apr 28;12:861807. doi: 10.3389/fonc.2022.861807

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Copyright © 2022 Wang, Huo, Zhang, Chen, Zhao, Shi, Xu and Wei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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METTL3 promoted GC angiogenesis. (A, B) HUVECs cultured with medium obtained from GC cells with METTL3 deficiency or overexpression. (C) Representative images of the CAM experiment from LV-shMETTL3 and LV-shNC group. (D) Representative images of the CAM experiment from LV-METTL3 and LV-NC group. The average number of new vessels was quantified. Scar bar = 50 μm, ***P < 0.001.