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MeRIP-seq and RNA-seq identified ADAMTS9 as a downstream target of METTL3. (A) ADAMTS9 and POSTN were selected as candidate genes after filtering the upregulated genes and reduced m6A peaks. (B) The m6A abundances on ADAMTS9 mRNA in AGS cells with METTL3 knockdown or not as examined by MeRIP-seq were plotted. (C) The expression level of ADAMTS9 in METTL3-decificent and -overexpression GC cells. ***P < 0.001.
