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. 2022 Apr 28;12:861807. doi: 10.3389/fonc.2022.861807

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Copyright © 2022 Wang, Huo, Zhang, Chen, Zhao, Shi, Xu and Wei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ADAMTS9 reversed the effects of METTL3 in GC. (A) The ADAMTS9 expressions were artificially reduced in METTL3 knockdown GC cells. (B) The cell viability of METTL3-knockdown GC cells was detected after ADAMTS9 suppression by CCK-8 assay. (C) The proliferation of METTL3-knockdown GC cells were detected after ADAMTS9 suppression by colony formation assay. (D) The angiogenesis ability of METTL3-knockdown GC cells were evaluated after ADAMTS9 suppression by tube formation assay. Scar bar = 50 μm, **P < 0.01, ***P < 0.001.