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. Author manuscript; available in PMC: 2022 Oct 5.
Published in final edited form as: Nat Neurosci. 2022 Apr 5;25(4):493–503. doi: 10.1038/s41593-022-01044-2

Extended Data Fig. 4. Neural differentiation from adult MTLE patients.

Extended Data Fig. 4

(a) Upper 3 panels: Tuj1+ (green) GFAP+ (red) newborn astroglia (marked by arrows) and Tuj1+ GFAP- cells (marked by arrowheads) present in neural differentiation cultures at 3-week (N = 6) and 6-week (N = 5) differentiation. Lower 3 panels: Tuj1+ (green) Prox1+ (red) newborn granule neurons (marked by arrows) and Tuj1+ Prox1- cells (marked by arrowheads) present in neural differentiation cultures at 3-week (N = 5) and 6-week (N = 5) differentiation. Scale-bar: 50μm (b) Tuj1- GFAP+ mature astroglia were rarely identified in N = 3 cases. Scale-bar: 50μm. (c) Percentage of Tuj1- GFAP+ mature astroglia at 3 (N = 6) - and 6-week (N = 5) differentiation. Graph represents s.e.m.