Hippocampal–parietal functional circuits predict number sense training gains. A, B, Scatter plots of the relationship between functional connectivity (FC) of the left (A) and right (B) hippocampus with the left IPS and changes in efficiency in symbolic quantity discrimination (efficiency gain) in children who received training (Training) and no-contact control group (Control). Greater FC with the left IPS predicts efficiency gain in the Training group (all ρ values > 0.40, all p values < 0.004), but not in the Control group (all |ρ| values < 0.21, all p values > 0.44). Target (IPS) regions of interest were identified using a 6 mm sphere centered on the peak voxel to estimate FC. L, Left, R, right.