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. 2022 Mar 9;5(1):ooac017. doi: 10.1093/jamiaopen/ooac017

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© The Author(s) 2022. Published by Oxford University Press on behalf of the American Medical Informatics Association.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Journey of real-world data from capturing in the NTD registry to analysis at the DPS. Diamonds indicate checkpoints of the data control framework. (1) Already during the data collection process, dropdown menus ensure consistency during the input procedures and multiple automated checks ensure that accurate data are uploaded to the server. (2) The data transfer process from the registry to the data processing site (DPS) contains multiple checkpoints to ensure the integrity of the transfer. (3) After arriving at the DPS, the data are uploaded into a secure and strictly access-controlled structured query language (SQL) database and undergo additional control steps in a process that ends with a dataset ready for analysis. DESTINY^®: DatabasE-aSsisted Therapy decIsioN support sYstem; DPS: data processing site; NTD: NeuroTransData.