TABLE 2.
Postpartum outcomes
| Outcome | Ibuprofen n = 50 | Acetaminophen n = 50 | P value |
|---|---|---|---|
| Duration of severe-range HTN, h, mean (95% CI)a | 35.3 (27.2−47.5) | 38.0 (29.4−51.3) | .3b |
| Time from delivery to last BP ≥150/100 mm Hg, h, mean (95% CI) | 58.3 (48.0−68.6) | 57.1 (45.8−68.5) | .9b |
| Time to BP control, h, mean (95% CI)c | 56.7 (45.1−71.2) | 68.8 (54.0−86.7) | .3d |
| Postpartum MAP, mean (SD) | 97.6 (6.2) | 97.3 (9.1) | .9e |
| Maximum postpartum SBP, mean (SD) | 168 (16) | 165 (15) | .3e |
| Maximum postpartum DBP, mean (SD) | 99 (10) | 96 (10) | .2e |
| Any postpartum BP ≥160/110 mm Hg, n (%) | 34 (68) | 31 (62) | .5f |
| Any postpartum meds for acute BP control, n (%) | 30 (60) | 26 (52) | .4f |
| Postpartum stay, d, mean (SD) | 3.8 (1.4) | 4.0 (1.3) | .5e |
| Postpartum stay extended for BP control, n (%) | 18 (36) | 23 (46) | .3f |
| On antihypertensives at discharge, n (%) | 33 (66) | 31 (62) | .7f |
BP, blood pressure; CI, confidence interval; DBP, diastolic blood pressure; HTN, hypertension; MAP, mean arterial pressure; SBP, systolic blood pressure.
a
Time from delivery to last BP ≥160/110 mm Hg;
b
Maximum likelihood test for exponential means;
c
Subgroup analysis in only patients who experienced any severe-range HTN, n = 31 in acetaminophen group and n = 34 in ibuprofen group;
d
Wald χ2 test;
e
Independent 2-sample t test;
f
χ2 Test.