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. 2022 Apr 28;13:880288. doi: 10.3389/fimmu.2022.880288

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Copyright © 2022 Li, Zhang, Liu, Fu, A, Chen, Wu and Dong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Higher 11LNCPS scores are associated with several cancer hallmarks and immunological characteristics of HCC. (A, B) GO enrichment (A) and KEGG pathway (B) analysis of differentially expressed genes (DEGs) between HCCs with higher and lower 11LNCPS scores. The heights of bars and sizes of dots represent the count of genes, while the colors represent the adjusted P-value. (C) Significantly enriched cancer hallmarks in HCCs with higher 11LNCPS scores, as analyzed by the GSEA. Red and blue dots indicate a pathway’s activation and suppression, respectively. The x-axis shows normalized enrichment scores (NES). All pathways with P values smaller than 0.05 are shown.