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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: J Proteome Res. 2022 Mar 11;21(4):1095–1104. doi: 10.1021/acs.jproteome.1c00966

Figure 2. Assessment of HSPB1 and APP for discriminating AD in five datasets obtained from brain regions with high AD pathology.

Figure 2.

(A) AUCs for HSPB1; (B) fold change for HSPB1; (C) AUCs for APP; (D) fold change for APP. P-values were calculated using paired t-tests. Abbreviations: AUC, are under the curve; HSPB1, heat shock protein β-1; NHW, non-Hispanic White; AA, African American; ROSMAP, Religious Orders Study and Rush Memory and Aging Project; MSBB, Mount Sinai Brain Bank; Pitt ADRC, University of Pittsburgh Alzheimer Disease Research Center; IPL, inferior parietal lobule; APP, amyloid-β precursor protein.