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. 2022 Apr 25;13:863959. doi: 10.3389/fphar.2022.863959

FIGURE 4.

FIGURE 4

No sex dysmorphism was observed in the REL-1017 effect on cingulate neuronal necrosis. Separate quantification of neuronal necrosis in female and male groups. No differences in neuronal necrosis quantification were observed between female and male REL-1017 treated rats. As expected, we observed a major severity of necrosis in female rats treated with MK-801 (p < 0.0001 at Day 3).