| Necrosis, Neuronal | |
| Severity Grade 1 (minimal) | <1% of neurons in a tissue/region affected |
| Severity Grade 2 (mild) | 1–5% of neurons in a tissue/region affected |
| Severity Grade 3 (moderate) | 5–15% of neurons in a tissue/region affected |
| Severity Grade 4 (marked) | 15–40% of neurons in a tissue/region affected |
| Severity Grade 5 (severe) | >40% of neurons in a tissue/region affected |
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