Appendix 3—table 2. Genetic effects and pharmaco-genetic interactions in study 2.

Columns are organized as in Table 1 of the main text. Volatile mismatch ERPs in the placebo group were positively modulated by CHAT polymorphism, and negatively modulated by COMT polymorphism.

Study 2: Genetic effects	cluster	${\displaystyle x\left[\mathrm{m}\mathrm{m}\right]}$	${\displaystyle y\left[\mathrm{m}\mathrm{m}\right]}$	${\displaystyle z\left[\mathrm{m}\mathrm{s}\right]}$	$t_{68/67}$	$Z_{\equiv }$	$p_{FWE}$	$k_E$	$t{w}_{sig}$[ms]
A volatile mismatch: PLA: pos. effect of CHAT	1	–13	–78	104	4.42	4.13	0.046	4	104–108
B volatile mismatch: PLA: neg. effect of COMT	1	4	45	192	5.31	4.84	0.003	53	180–200