FIGURE 6.
Effects of lactobacillus intravaginal administration on chlamydia-induced mouse genital and intestinal tract pathologies, following intravaginal infection with C. muridarum. (A) The groups of the mice were treated as described in the Figure 3 legend. The urogenital tract tissues were subjected to histological section analyses for observing inflammatory pathologies via H&E staining. Sections of oviduct and uterine horn tissues from the mice in each group were examined for both inflammatory infiltration (IN) and lumenal dilatation (DI) (red arrows), whereas small and large intestine tissues for inflammatory infiltration. The extent of inflammation (B) and dilatation (C) was semiquantitatively scored as described in the method section. The scores were calculated as the means and standard deviations for each group. *p < 0.05, **p < 0.01, and ***p < 0.001 vs. the Cm group (one-way ANOVA).