Figure 4.

The expression of TH and GPX4 was decreased, while the expression of SNX5 was increased in the PD cell model. (a) PC-12 cells were untreated or treated with 40 μM 6-OHDA for 24 h. The expression of TH, GPX4, and SNX5 was detected by Western blotting. (b) MDA Assay was used to detect the concentration MDA in PC-12 cells was induced by 6-OHDA. (c) GSH/GSSG ratio in vitro PD was detected by GSH/GSSG Assay. Data were expressed as mean ± S.D.; three independent replicates of the experiment (^∗∗∗p < 0.05).