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The effects of erastin and fer-1 on PD cell model. PC-12 cells were induced with 40 μM 6-OHDA in combination with an inducer (1 μM erastin) or inhibitor (2.5 μM fer-1) of ferroptosis for 24 h. The expression of GPX4, TH, and SNX5 was detected by Western blotting (a) and (b). Data were expressed as mean ± S.D.; three independent replicates of the experiment (∗∗∗p < 0.05).
